产品货号:
Z38220
中文名称:
HLA-DRA抗体
英文名称:
Anti-HLA-DRA Antibody (Clone#5B13F7)
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-HLA-DRA Antibody (Clone#5B13F7) |
指标别名 | HLA DRA;HLA DRA1;HLA-DR;HLA-DRA;MHC class II antigen DRA |
克隆性 | Monoclonal |
检验物种 | human |
应用范围 | WB,IHC,FCM |
基因名称 | HLA-DRA |
克隆号 | 5B13F7 |
抗体来源 | Mouse |
抗体类型 | IgG2b |
免疫原 | E.coli-derived human HLA-DR/HLA-DRA recombinant protein (Position:I26-L254). |
实际分子量 | 35~37KD |
成分 | Each vial contains 4mg Trehalose,0.9mg NaCl and 0.2mg Na2HPO4. |
纯化方式 | protein G/A purified |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | HLA class II histocompatibility antigen,DR alpha chain?is a?protein?that in humans is encoded by the HLA-DRA?gene.It is mapped to 6p21.32.HLA-DRA is one of the HLA class II alpha chain paralogues.This class II molecule is a heterodimer consisting of an alpha and a beta chain,both anchored in the membrane.It plays a central role in the immune system by presenting peptides derived from extracellular proteins.Class II molecules are expressed in antigen presenting cells (APC:B lymphocytes,dendritic cells,macrophages).The alpha chain is approximately 33~35kDa and its gene contains 5 exons.Exon 1 encodes the leader peptide,exons 2 and 3 encode the two extracellular domains,and exon 4 encodes the transmembrane domain and the cytoplasmic tail.DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1,DRB3,DRB4 and DRB5. |
Uniprot ID | P01903 |
推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (ZN1928) for Western blot,and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (ZN1866) for IHC(P) and ICC. |
基因名全称 | major histocompatibility complex,class II,DR alpha |
蛋白名全称 | HLA class II histocompatibility antigen,DR alpha chain |
推荐稀释比 | Western blot(WB) 1:500~2000 Flow Cytometry (FCM) 1~3μg/1×106 cells Immunohistochemistry in paraffin section (IHC) 1:50~400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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